H2 Human Histamine GPCR Cell Based Antagonist cAMP LeadHunter Assay - FR

Background Information:

Histamine receptors belong to the superfamily of G protein-coupled seven transmembrane proteins. G-protein-coupled receptors constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. Histamine receptors are found in most peripheral tissue and within the central nervous system.

Family:

GPCR

Sub Family:

Histamine

Class:

Class A

Protein Name:

H2

Uniprot Number:

P25021

Protein Aliases:

HH2R|Gastric receptor I

Gene Name:

HRH2

Gene ID:

3274

Accession Number:

XM_005265904

Organism:

Human

Construct Details:

Recombinant

Cell Type:

CHO-K1