CCK2 (CCKB) Human Cholecystokinin GPCR Cell Based Agonist cAMP LeadHunter Assay - FR

Background Information:

Cholecystokinin receptors belong to the superfamily of G protein-coupled seven transmembrane proteins. G-protein-coupled receptors constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. Cholecystokinin CCK2 receptors are widely distributed in the brain, with highest concentrations in the striatum, cerebral cortex and limbic system, but can also be found in the stomach.

Family:

GPCR

Sub Family:

Cholecystokinin

Class:

Class A

Protein Name:

CCK2 (CCKB)

Uniprot Number:

P32239

Protein Aliases:

CCK-BR|Cholecystokinin-2 receptor|CCK2-R

Gene Name:

CCKBR

Gene ID:

887

Gene Aliases:

CCKRB

Accession Number:

NM_176875

Organism:

Human

Construct Details:

Recombinant

Cell Type:

CHO-K1