Biological Information

Family:

GPCR

Sub Family:

Corticotropin-Releasing Factor

Class:

Class B

Protein Name:

CRF2

Uniprot Number:

Q13324

Protein Aliases:

CRF-R2|CRFR-2|Corticotropin-releasing hormone receptor 2|CRH-R-2|CRH-R2

Gene Name:

CRHR2

Gene ID:

1395

Gene Aliases:

CRF2|CRF-RB|HM-CRF|CRF2R|CRH2R

Accession Number:

XM_011515127

Organism:

Human

Construct Details:

Recombinant

Cell Type:

HEK293

Assay Information

Assay Type:

Functional

Assay Sub Type:

Cell Based

Functional Mode:

Agonist

Detection Method:

HTRF

Testing Information

Incubation:

30 min at RT

Control Activator:

CRF (human)

Test Concentration / Dose:

Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.

Test Sample Requirements:

Minimum for 1) Screen: 60 µL of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM finµL testing. 2) Dose Response: 90 µL of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.

Minimum Order Quantity:

16

Turnaround Time

Standard:

15 Business Days

Reference Compound Data

PubChem ID

16132263

Name

Urotensin I

Measurement

1.2nM - EC50

PubChem ID

16132357

Name

CRF (human)

Measurement

37nM - EC50

PubChem ID

Name

sauvagine

Measurement

0.34nM - EC50

PubChem ID

Name

urocortin

Measurement

0.33nM - EC50

Clinical Relevance

Therapeutic Area:

Inflammation/Allergy

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault

RELATED SOLUTIONS

Item: 2086
Item: G066