APJ Human Apelin GPCR Binding Agonist Radioligand LeadHunter Assay - FR

Background Information:

APJ (apelin) belongs to the superfamily of seven transmembrane G-protein-coupled receptors, which constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. APJ receptors are found in the lung, heart, and hypothalamic region.

Family:

GPCR

Sub Family:

Apelin

Class:

Class A

Protein Name:

APJ

Uniprot Number:

P35414

Protein Aliases:

APJ (apelin) receptor

Gene Name:

APLNR

Gene ID:

187

Gene Aliases:

FLJ90771|APJ|APJR

Accession Number:

NM_005161

Organism:

Human

Construct Details:

Recombinant