Biological Information

Family:

GPCR

Sub Family:

Glucagon

Class:

Class B

Protein Name:

GHRH

Uniprot Number:

Q02643

Protein Aliases:

Growth hormone-releasing factor receptor|GRF receptor|GRFR

Gene Name:

GHRHR

Gene ID:

2692

Accession Number:

NM_000823

Organism:

Human

Construct Details:

Recombinant

Cell Type:

CHO-K1

Assay Information

Assay Type:

Functional

Assay Sub Type:

Cell Based

Functional Mode:

Antagonist

Detection Method:

HTRF

Testing Information

Incubation:

10 min at RT

Control Inhibitor:

Ac[Tyr1,D-Arg2]GRF 1-29 amide human

Control Activator:

human GHRF(1-29) (10 nM)

Test Concentration / Dose:

Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.

Test Sample Requirements:

Minimum for 1) Screen: 60 µL of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM finµL testing. 2) Dose Response: 90 µL of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.

Minimum Order Quantity:

16

Turnaround Time

Standard:

15 Business Days

Reference Compound Data

PubChem ID

Name

[des-His1-Glu9]-glucagon amide

Measurement

- IC50

PubChem ID

Name

JV-1-36

Measurement

8.4nM - IC50

PubChem ID

Name

JV-1-38

Measurement

15.5nM - IC50

PubChem ID

Name

Ac[Tyr1,D-Arg2]GRF 1-29 amide human

Measurement

43nM - IC50

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault

RELATED SOLUTIONS

Item: 2236
Item: G071