alpha2A Human Adrenoceptor GPCR GTPgammaS Antagonist LeadHunter Assay - TW

Background Information:

Adrenoreceptors belong to the superfamily of G protein-coupled seven transmembrane proteins. G-protein-coupled receptors constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. Adrenoreceptors are found in most peripheral tissue and within the central nervous system. .

Family:

GPCR

Sub Family:

Adrenoceptor

Class:

Class A

Protein Name:

alpha2A

Uniprot Number:

P08913

Protein Aliases:

alpha-2AAR subtype C10| alpha-2A-adrenergic receptor

Gene Name:

ADRA2A

Gene ID:

150

Gene Aliases:

ADRA2R|ADRAR

Accession Number:

NM_000681

Organism:

Human

Construct Details:

Full Length, Recombinant

Cell Type:

Chem-1