ERalpha Human Estrogen NHR Functional Antagonist Coactivator LeadHunter Assay - TW

Background Information:

Estrogens, produced by ovaries and testis, affect growth and differentiation of many target tissues. These include the male and female reproductive tissues (mammary gland, uterus, ovary, and prostate). Estrogens have also been implicated in the physiology of the bone, cardiovascular tissues, and the brain. Two distinct estrogen receptors (ERα and ERß) bind estrogen as well as other agonists and antagonists. Estrogen receptor is a member of the super family of nuclear receptor that show a similar structure and mode of action.

Family:

NHR

Sub Family:

Estrogen

Class:

Steroid

Protein Name:

ERalpha

Uniprot Number:

P03372

Protein Aliases:

ER-alpha|Estradiol receptor|Nuclear receptor subfamily 3 group A member 1

Gene Name:

ESR1

Gene ID:

2099

Gene Aliases:

NR3A1|Era

Accession Number:

NM_001328100

Organism:

Human

Construct Details:

LBD, Recombinant