EP1 Human Prostanoid GPCR Cell Based Agonist IP1 LeadHunter Assay - TW

Background Information:

Prostanoid receptors belong to the superfamily of G protein-coupled seven transmembrane proteins. G-protein-coupled receptors constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. The EP1 prostanoid receptor is activated by prostaglandin E2 (PGE2) and it is most highly expressed in Kidney, myometrium and GI smooth muscle.

Family:

GPCR

Sub Family:

Prostanoid

Class:

Class A

Protein Name:

EP1

Uniprot Number:

P34995

Protein Aliases:

PGE2 receptor EP1 subtype|Prostanoid EP1 receptor

Gene Name:

PTGER1

Gene ID:

5731

Gene Aliases:

EP1

Accession Number:

NM_000955

Organism:

Human

Construct Details:

Full Length, Recombinant

Cell Type:

HEK293