OVERVIEW
DOCUMENTS/REFERENCES
Biological Information
Background Information:
Poorly soluble compounds can dramatically reduce productivity in drug discovery and development. Eurofins solubility assays involve assessment of kinetic solubility (from DMSO stock solution) using a shake-flask technique in a plate format and LCUV or nephelometric analysis. Solubility information helps in interpreting results from other in vitro assays, recognizing compounds that are solubility limited, and prioritizing compounds for further development.
Assay Information
Assay Type:
Physiochemical
Detection Method:
HPLC-UV/VIS
Measured Response:
Peak Area Response
Testing Information
Test Concentration / Dose:
Assay is performed with a single concentration of 200 µM using 2 replicates
Test Sample Requirements:
Minimum for 1) Screen: 100 μl of 10 mM stock -OR- 1 to 2 mg (pre-weighed). 2) Dose Response: 250 μl of 10 mM stock -OR- 1.5 to 2 mg (pre-weighed).
Turnaround Time
Standard:
10 Business Days
Additional Information
Brand:
Cerep
Testing Location:
Spain - Murcia
RELATED SOLUTIONS
Aqueous solubility (simulated gastric fluid) - ES
Item: 5220
Aqueous solubility (simulated intestinal fluid) - ES
Item: 5221
Questions? Contact Us
You can easily get in touch with a Eurofins Discovery Expert or get help from our Customer Service team. Reach out with questions, or to discuss your specific discovery challenges.
