Biological Information

Background Information:

Evaluation of two compounds in any BioMAP system, individually and in combination. The CASMNo system is comprised of coronary artery smooth muscle cells and is the nonstimulated control for the CASM3C system.

Organism:

Human

Assay Information

Assay Type:

Functional

Assay Sub Type:

Cell Based

Testing Information

Test Concentration / Dose:

Two test agents profiled alone at four concentrations, and in combination in a four-by-four matrix, in triplicate.

Test Sample Requirements:

For Small Molecules: 350uL of a 1000X stock based on the top concentration being tested & standard 3-fold dilutions per system and per Combo. For Biologics: 3.5mL of a 100X stock in PBS or water, based on the top concentration being tested & standard 3-fold dilutions per system and per Combo

Turnaround Time

Standard:

40 Business Days

Clinical Relevance

Therapeutic Area:

Oncology/Immuno-Oncology

Additional Information

Brand:

BioMAP

Testing Location:

USA - St Charles, MO