Biological Information

Background Information:

Evaluation of two compounds in any BioMAP system, individually and in combination. The VascC system is comprised of vascular endothelial cells and peripheral blood mononuclear cells, stimulated via the T cell receptor for 48-hrs and is the cancer cell line negative version of the VascHT29 system.

Organism:

Human

Assay Information

Assay Type:

Functional

Assay Sub Type:

Cell Based

Testing Information

Test Concentration / Dose:

Two test agents profiled alone at four concentrations, and in combination in a four-by-four matrix, in triplicate.

Test Sample Requirements:

For Small Molecules: 350uL of a 1000X stock based on the top concentration being tested & standard 3-fold dilutions per system and per Combo. For Biologics: 3.5mL of a 100X stock in PBS or water, based on the top concentration being tested & standard 3-fold dilutions per system and per Combo

Turnaround Time

Standard:

40 Business Days

Clinical Relevance

Therapeutic Area:

Oncology/Immuno-Oncology

Additional Information

Brand:

BioMAP

Testing Location:

USA - St Charles, MO