Biological Information
Background Information:
Evaluation of two compounds in any BioMAP system, individually and in combination. The VascC system is comprised of vascular endothelial cells and peripheral blood mononuclear cells, stimulated via the T cell receptor for 48-hrs and is the cancer cell line negative version of the VascHT29 system.
Organism:
Human
Assay Information
Assay Type:
Functional
Assay Sub Type:
Cell Based
Testing Information
Test Concentration / Dose:
Two test agents profiled alone at four concentrations, and in combination in a four-by-four matrix, in triplicate.
Test Sample Requirements:
For Small Molecules: 350uL of a 1000X stock based on the top concentration being tested & standard 3-fold dilutions per system and per Combo. For Biologics: 3.5mL of a 100X stock in PBS or water, based on the top concentration being tested & standard 3-fold dilutions per system and per Combo
Turnaround Time
Standard:
40 Business Days
Clinical Relevance
Therapeutic Area:
Oncology/Immuno-Oncology
Additional Information
Brand:
BioMAP
Testing Location:
USA - St Charles, MO