Biological Information

Background Information:

High quality RNA (250 ng) prepared from individual BioMAP systems, provided to clients for their own downstream gene expression experiments. The SAg system is comprised of venular endothelial cells and peripheral blood mononuclear cells. It models Th1 type chronic inflammation and T cell effector responses related to T cell proliferation and activation in the context of the vascular endothelium. Modeling chronic inflammation of the Th1 type and T cell effector responses, the SAg system is relevant for T-cell driven inflammatory conditions including organ transplantation, rheumatoid arthritis, psoriasis, Crohn's disease, and hematological oncology.

Organism:

Human

Assay Information

Assay Type:

Functional

Assay Sub Type:

Cell Based

Testing Information

Test Sample Requirements:

For Small Molecules: 240uL of a 1000X stock based on the top concentration being tested & standard 3-fold dilutions. For Biologics: 2.4mL of a 100X stock in PBS or water, based on the top concentration being tested & standard 3-fold dilutions

Minimum Order Quantity:

4

Turnaround Time

Standard:

40 Business Days

Clinical Relevance

Therapeutic Area:

Autoimmune

Additional Information

Brand:

BioMAP

Testing Location:

USA - St Charles, MO