OVERVIEW
DOCUMENTS/REFERENCES
Biological Information
Background Information:
Panel of 12 BioMAP systems consisting of human primary cell-based tissue and disease models to correlate biological outcome with clinical response; includes nine toxicity signatures predictive of adverse outcomes. Quantitative readouts of 148 translational biomarkers inform BioMAP profiles as well as the BioMAP Toxicity Signature Analysis (TSA). BioMAP TSA was built using the comprehensive BioMAP Reference Database, curated for clinically approved and experimental drugs with similar known toxicities or adverse effects. Data mining tools identified common biomarkers from BioMAP profile data that were then developed into toxicity signatures. The nine signatures include: Acute Toxicity, Immunosuppression, Skin Irritation, Liver Toxicity, Organ Toxicity, Skin Rash, Skin Sensitization, Thrombosis, and Vascular Toxicity.
No. of Assays on Panel:
12
Assays on Panel:
Family
Name
BioMAP Systems ELECT Menu 1 (3C)
Item
89-0003-0001
Protein
Organism
Human
Assay Sub Type
Cell Based
Family
Name
BioMAP Systems ELECT Menu 1 (4H)
Item
89-0003-0002
Protein
Organism
Human
Assay Sub Type
Cell Based
Family
Name
BioMAP Systems ELECT Menu 1 (LPS)
Item
89-0003-0003
Protein
Organism
Human
Assay Sub Type
Cell Based
Family
Name
BioMAP Systems ELECT Menu 1 (SAg)
Item
89-0003-0004
Protein
Organism
Human
Assay Sub Type
Cell Based
Family
Name
BioMAP Systems ELECT Menu 3 (BT)
Item
89-0003-0005
Protein
Organism
Human
Assay Sub Type
Cell Based
Family
Name
BioMAP Systems ELECT Menu 2 (BF4T)
Item
89-0003-0006
Protein
Organism
Human
Assay Sub Type
Cell Based
Family
Name
BioMAP Systems ELECT Menu 2 (BE3C)
Item
89-0003-0007
Protein
Organism
Human
Assay Sub Type
Cell Based
Family
Name
BioMAP Systems ELECT Menu 1 (CASM3C)
Item
89-0003-0008
Protein
Organism
Human
Assay Sub Type
Cell Based
Family
Name
BioMAP Systems ELECT Menu 1 (HDF3CGF)
Item
89-0003-0009
Protein
Organism
Human
Assay Sub Type
Cell Based
Family
Name
BioMAP Systems ELECT Menu 1 (KF3CT)
Item
89-0003-0010
Protein
Organism
Human
Assay Sub Type
Cell Based
Family
Name
BioMAP Systems ELECT Menu 1 (MyoF)
Item
89-0003-0011
Protein
Organism
Human
Assay Sub Type
Cell Based
Family
Name
BioMAP Systems ELECT Menu 3 (lMphg)
Item
89-0003-0012
Protein
Organism
Human
Assay Sub Type
Cell Based
Organism:
Human
Assay Information
Assay Type:
Functional
Assay Sub Type:
Cell Based
Testing Information
Test Sample Requirements:
For Small Molecules: 150uL of a 1000X stock based on the top concentration being tested & standard 3-fold dilutions. For Biologics: 1.5mL of a 100X stock in PBS or water, based on the top concentration being tested & standard 3-fold dilutions
Turnaround Time
Standard:
30 Business Days
Additional Information
Brand:
BioMAP
Testing Location:
USA - St Charles, MO
Questions? Contact Us
You can easily get in touch with a Eurofins Discovery Expert or get help from our Customer Service team. Reach out with questions, or to discuss your specific discovery challenges.
