alpha1A Human Adrenoceptor GPCR Cell Based Agonist & Antagonist Calcium Flux LeadHunter Assay - FR

Background Information:

Adrenoreceptors belong to the superfamily of G protein-coupled seven transmembrane proteins. G-protein-coupled receptors constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. Adrenoreceptors are found in most peripheral tissue and within the central nervous system.

No. of Assays on Panel:

2

Family:

GPCR

Sub Family:

Adrenoceptor

Class:

Class A

Protein Name:

alpha1A

Uniprot Number:

P35348

Protein Aliases:

Alpha-1A adrenoceptor|Alpha-1C adrenergic receptor|Alpha-adrenergic receptor 1c

Gene Name:

ADRA1A

Gene ID:

148

Gene Aliases:

ADRA1L1|ADRA1C

Organism:

Human

Cell Type:

CHO-K1