CCK1 (CCKA) Human Cholecystokinin GPCR Cell Based Agonist & Antagonist cAMP LeadHunter Assay - FR

Background Information:

Cholecystokinin receptors belong to the superfamily of G protein-coupled seven transmembrane proteins. G-protein-coupled receptors constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. Cholecystokinin CCK1 receptors are found in high concentrations in the gastrointestinal tract and a few discrete brain regions.

No. of Assays on Panel:

2

Family:

GPCR

Sub Family:

Cholecystokinin

Class:

Class A

Protein Name:

CCK1 (CCKA)

Uniprot Number:

P32238

Protein Aliases:

CCK-AR|Cholecystokinin-1 receptor|CCK1-R

Gene Name:

CCKAR

Gene ID:

886

Organism:

Human

Cell Type:

CHO-K1