MC3 Human Melanocortin GPCR Cell Based Agonist & Antagonist cAMP LeadHunter Assay - FR

Background Information:

Melanocortins belong to the superfamily of G protein-coupled seven transmembrane proteins. G-protein-coupled receptors constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. The melanocortin MC1 receptor is made primarily in melanocytes, MC2 in adrenal cortex, MC3 and MC4 almost exclusively neuronal, and MC5 in exocrine gland cells.

No. of Assays on Panel:

2

Family:

GPCR

Sub Family:

Melanocortin

Class:

Class A

Protein Name:

MC3

Uniprot Number:

P41968

Gene Name:

MC3R

Gene ID:

4159

Gene Aliases:

MC3

Organism:

Human

Cell Type:

CHO-K1