NK2 Human Tachykinin GPCR Cell Based Agonist & Antagonist Calcium Flux LeadHunter Assay - FR

Background Information:

Tachykinins belong to the superfamily of G protein-coupled seven transmembrane proteins. G-protein-coupled receptors constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. Tachykinin receptors are found in most peripheral tissue and within the central nervous system.

No. of Assays on Panel:

2

Family:

GPCR

Sub Family:

Tachykinin

Class:

Class A

Protein Name:

NK2

Uniprot Number:

P21452

Protein Aliases:

NK-2 receptor|NK-2R|Neurokinin A receptor|Tachykinin receptor 2

Gene Name:

TACR2

Gene ID:

6865

Gene Aliases:

SKR|NK2R|NKNAR|TAC2R

Organism:

Human

Cell Type:

CHO-K1