UT (GPR14) Human Urotensin GPCR Cell Based Agonist & Antagonist Calcium Flux LeadHunter Assay - FR

Background Information:

Urotensin II receptors belong to the superfamily of G protein-coupled seven transmembrane proteins. G-protein-coupled receptors constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. Urotensin II receptors are found in the brain stem and spinal cord as well as peripheral tissue, especially heart and vasculature.

No. of Assays on Panel:

2

Family:

GPCR

Sub Family:

Urotensin

Class:

Class A

Protein Name:

UT (GPR14)

Uniprot Number:

Q9UKP6

Protein Aliases:

G-protein coupled receptor 14|Urotensin II receptor|UR-II-R

Gene Name:

UTS2R

Gene ID:

2837

Gene Aliases:

GPR14

Organism:

Human

Cell Type:

CHO-K1