Phosphatase Profiler LeadHunter Panel - TW

Background Information:

Protein phosphatases (PPs) are the primary effectors of dephosphorylation and can be grouped into three main classes as serine-threonine phosphatase, classical tyrosine phosphatase and dual-specificity phosphatase based on their substrate specificity. Phosphatases are signal transducing enzymes to modulate the activities of the proteins in cellular process, including metabolism, gene transcription, cell-cycle progression, cytoskeletal rearrangement, protein-protein interactions, protein stability, cell movement and apoptosis. Target protein phosphatases for cellular function with perturbations may be potential therapeutic drugs for various diseases such as autoimmune, infection, inflammation, obesity, diabetes, neurodegeneration and cancer diseases.

No. of Assays on Panel:

22