ACKR3 (CXCR7) Human Chemokine GPCR Cell Based Agonist Arrestin LeadHunter Assay - US

Background Information:

PathHunter β-Arrestin GPCR cell lines are engineered to co-express the ProLink™ (PK) tagged GPCR and the Enzyme Acceptor (EA) tagged β-Arrestin. Activation of the GPCR-PK induces β-Arrestin-EA recruitment, forcing complementation of the two β-galactosidase enzyme fragments (EA and PK). The resulting functional enzyme hydrolyzes substrate to generate a chemiluminescent signal.

Family:

GPCR

Sub Family:

Chemokine

Class:

Class A

Protein Name:

ACKR3 (CXCR7)

Uniprot Number:

P25106

Protein Aliases:

CXC-R7|CXCR-7|Chemokine orphan receptor 1|G-protein coupled receptor 159|G-protein coupled receptor RDC1 homolog|RDC-1

Gene Name:

ACKR3

Gene ID:

57007

Gene Aliases:

CMKOR1|CXCR7|GPR159|RDC1

Accession Number:

NM_020311.2

Organism:

Human

Cell Type:

CHO-K1