C3aR Human Complement Peptide GPCR Cell Based Agonist Arrestin LeadHunter Assay - US

Background Information:

PathHunter β-Arrestin GPCR cell lines are engineered to co-express the ProLink™ (PK) tagged GPCR and the Enzyme Acceptor (EA) tagged β-Arrestin. Activation of the GPCR-PK induces β-Arrestin-EA recruitment, forcing complementation of the two β-galactosidase enzyme fragments (EA and PK). The resulting functional enzyme hydrolyzes substrate to generate a chemiluminescent signal.

Family:

GPCR

Sub Family:

Complement Peptide

Class:

Class A

Coupling:

Gi/Go

Protein Name:

C3aR

Uniprot Number:

Q16581

Protein Aliases:

C3a-R

Gene Name:

C3AR1

Gene ID:

719

Gene Aliases:

C3AR|AZ3B|C3R1|HNFAG09

Accession Number:

NM_004054.2

Organism:

Human

Cell Type:

U2OS