CCR2 Human Chemokine GPCR Cell Based Calcium Flux LeadHunter Assay - FR

Background Information:

Chemokine receptors belong to the superfamily of G protein-coupled seven transmembrane proteins. G-protein-coupled receptors constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. Chemokine receptors are primarily distributed on cells involved in immune and inflammatory function.

No. of Assays on Panel:

2

Family:

GPCR

Sub Family:

Chemokine

Class:

Class A

Protein Name:

CCR2

Uniprot Number:

P41597

Organism:

Human