OVERVIEW
DOCUMENTS/REFERENCES
Biological Information
No. of Assays on Panel:
58
Assays on Panel:
Family
Kinase
Name
p38alpha (SAPK2A) Human CMGC Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-251KP
Protein
p38alpha (SAPK2A)
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
Akt1 (PKBalpha) Human AGC Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-276KP
Protein
Akt1 (PKBalpha)
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
GSK3beta (GSK3B) Human CMGC Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-306KP
Protein
GSK3beta
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
PRAK (MAPKAPK5) Human CAMK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-334KP
Protein
PRAK
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
MAPKAPK2 Human CAMK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-337KP
Protein
MAPKAPK2
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
CHK1 (CHEK1) Human CAMK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-346KP
Protein
CHK1
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
c-Raf (Raf-1) (RAF1) Human TKL Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-352KP
Protein
c-Raf (Raf-1)
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
MEK1 Human STE Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-429KP
Protein
MEK1
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
PKACalpha Human AGC Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-440KP
Protein
PKACalpha
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
Fyn Human TK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-441KP
Protein
Fyn
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
PKCtheta (PRKCQ) Human PKC Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-444KP
Protein
PKCtheta
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
CDK2/CyclinA Human CMGC Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-448KP
Protein
CDK2
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
CDK1/CyclinB Human CMGC Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-450KP
Protein
CDK1
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
IKKalpha Human Other Protein Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-461KP
Protein
IKKalpha
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
PDGFRbeta (PDGFRB) Human RTK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-463KP
Protein
PDGFRbeta
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
IGF1R Human RTK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-465KP
Protein
IGF1R
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
CDK7/CyclinH Human CMGC Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-476KP
Protein
CDK7
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
PAK2 Human STE Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-481KP
Protein
PAK2
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
PKCalpha Human PKC Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-484KP
Protein
PKCalpha
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
p70S6K (S6K1) (T412E) Human AGC Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-486KP
Protein
p70S6K
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
RSK1 Human AGC Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-509KP
Protein
RSK1
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
LYN Human TK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-510KP
Protein
LYN
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
Aurora-A (AURKA) Human Other Protein Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-511KP
Protein
Aurora-A
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
CDK6/CyclinD3 Human CMGC Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-519KP
Protein
CDK6
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
Abl (ABL1) Human TK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-529KP
Protein
Abl
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
EGFR Human RTK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-531KP
Protein
EGFR
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
TYRO3 (RSE) Human RTK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-535KP
Protein
TYRO3 (RSE)
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
NEK2 Human Other Protein Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-545KP
Protein
NEK2
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
EphB4 Human RTK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-554KP
Protein
EphB4
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
ALK Human RTK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-555KP
Protein
ALK
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
PI3Kgamma (PIK3CG) (p120gamma) Human PtdIns(4,5)P 3-Kinase Enzymatic TR-FRET [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-558KP
Protein
PI3Kgamma
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
SRPK1 Human CMGC Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-564KP
Protein
SRPK1
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
Plk3 Human Other Protein Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-572KP
Protein
PLK3
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
Pim1 Human CAMK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-573KP
Protein
Pim1
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
IRAK4 Human TKL Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-599KP
Protein
IRAK4
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
TAK1 Human TKL Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-600KP
Protein
TAK1
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
ROCK1 Human AGC Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-601KP
Protein
ROCK1
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
PI3Kalpha (PIK3CA) (p110a/p85a) Human PtdIns(4,5)P 3-Kinase Enzymatic TR-FRET [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-602KP
Protein
PI3Kalpha
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
PI3Kbeta (PIK3CB) (p110b/p85a) Human PtdIns(4,5)P 3-Kinase Enzymatic TR-FRET [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-603KP
Protein
PI3Kbeta
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
PI3Kdelta (PIK3CD) (p110d/p85a) Human PtdIns(4,5)P 3-Kinase Enzymatic TR-FRET [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-604KP
Protein
PI3Kdelta
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
ASK1 Human STE Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-606KP
Protein
ASK1
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
MSK2 (RPS6KA4) Human AGC Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-616KP
Protein
MSK2
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
MST1 Human STE Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-624KP
Protein
MST1
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
KDR (VEGFR2) (KDR) Human RTK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-630KP
Protein
KDR (VEGFR2)
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
EphA5 Human RTK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-639KP
Protein
EphA5
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
JAK2 Human TK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-640KP
Protein
JAK2
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
eEF-2K Human Alpha Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-654KP
Protein
eEF-2K
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
CaMK1alpha (CAMK1) Human CAMK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-663KP
Protein
CaMK1alpha
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
MNK2 (MKNK2) Human CAMK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-664KP
Protein
MNK2
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
DRAK1 Human CAMK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-668KP
Protein
DRAK1
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
CDK9/CyclinT1 Human CMGC Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-685KP
Protein
CDK9
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
LOK Human STE Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-686KP
Protein
LOK
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
PKG1 (PRKG1) (alpha) Human AGC Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-688KP
Protein
PKG1
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
CK2alpha2 (CSNK2A2) Human Other Protein Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-689KP
Protein
CK2alpha2
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
MLK1 Human TKL Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-690KP
Protein
MLK1
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
CK1gamma1 (CSNK1G1) Human CK1 Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-711KP
Protein
CK1gamma1
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
mTOR Human PIKK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-769KP
Protein
mTOR
Organism
Human
Assay Sub Type
Enzymatic
Family
Kinase
Name
AMPKalpha1 Human CAMK Kinase Enzymatic Radiometric [Km ATP] KinaseProfiler LeadHunter Assay - FR
Item
14-840KP
Protein
AMPKalpha1
Organism
Human
Assay Sub Type
Enzymatic
Family:
Kinase
Assay Information
Assay Type:
Biochemical
Assay Sub Type:
Enzymatic
Functional Mode:
Antagonist
Testing Information
Procedure Summary:
ATP concentration is set around the kinase Km (±15 µM), with a minimum of 10 µM.
Test Sample Requirements:
Please provide compounds dissolved in 100% DMSO (PBS or HBSS prohibited).
Stock solution should be ≥50× the final assay concentration (a 10 mM stock is also acceptable).
Required volume:
– <60 kinase assays: 120 µL of 50× stock
– ≥60 assays: 420 µL of 50× stock
If you supply 10 mM stocks or powder (pre-weighed), we will apply the appropriate conversion.
For batches of ~50 compounds supplied as solids, the TAT will be extended.
Turnaround Time
Standard:
6 Business Days
Additional Information
Brand:
LeadHunter
Testing Location:
KP - France - Celle L'Evescault
Questions? Contact Us
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