OVERVIEW
DOCUMENTS/REFERENCES
Biological Information
Background Information:
The new Endocrine Disruption (ED) panel (item # P402) is a fast and cost-effective alternative to existing assays to predict the potential endocrine disruption value of your ingredients, chemicals or compounds in the early stages of product development using robust drug discovery gold-standard profiling tools & assays (11 NHRs, Aromatase, TPO, reductase) for early risk mitigation.
No. of Assays on Panel:
14
Assays on Panel:
Family
Oxidoreductase
Name
Steroid 5 alpha-Reductase Rat Enzymatic LeadHunter Assay - TW
Item
193600
Protein
Organism
Rat
Assay Sub Type
Enzymatic
Family
NHR
Name
PR Human Progesterone NHR Binding Agonist Radioligand LeadHunter Assay - FR
Item
2341
Protein
PR
Organism
Human
Assay Sub Type
Binding
Family
NHR
Name
PXR Human NHR Binding Agonist Radioligand LeadHunter Assay - FR
Item
2538
Protein
PXR
Organism
Human
Assay Sub Type
Binding
Family
NHR
Name
TR (Non-Selective) Rat Thyroid Hormone NHR Binding Agonist Radioligand LeadHunter Assay - TW
Item
285900
Protein
Organism
Rat
Assay Sub Type
Binding
Family
NHR
Name
CAR Human NHR Functional Agonist Coactivator LeadHunter Assay - TW
Item
307300-0
Protein
CAR
Organism
Human
Assay Sub Type
Protein-Protein Interaction
Family
NHR
Name
CAR Human NHR Functional Antagonist Coactivator LeadHunter Assay - TW
Item
307300-1
Protein
CAR
Organism
Human
Assay Sub Type
Protein-Protein Interaction
Family
CYP450
Name
CYP19A1 Human CYP450 Enzymatic LeadHunter Assay - FR
Item
4407
Protein
CYP19A1
Organism
Human
Assay Sub Type
Enzymatic
Family
Endocrine System
Name
Thyroid Peroxidase Rat Hormone Turnover Enzymatic LeadHunter Assay - FR
Item
4419
Protein
Thyroid Peroxidase
Organism
Rat
Assay Sub Type
Enzymatic
Family
NHR
Name
GR Human Glucocorticoid NHR Binding Agonist Radioligand LeadHunter Assay - FR
Item
469
Protein
GR
Organism
Human
Assay Sub Type
Binding
Family
Name
AhR Nuclear Receptor Assay (human, agonist, 1 conc.) - US
Item
4793
Protein
Organism
Human
Assay Sub Type
Cell Based
Family
NHR
Name
ERalpha Human Estrogen NHR Binding Agonist Radioligand LeadHunter Assay - FR
Item
5484
Protein
ERalpha
Organism
Human
Assay Sub Type
Binding
Family
NHR
Name
PPARalpha Human NHR Binding Agonist Radioligand LeadHunter Assay - FR
Item
640
Protein
PPARalpha
Organism
Human
Assay Sub Type
Binding
Family
NHR
Name
PPARgamma Human NHR Binding Agonist Radioligand LeadHunter Assay - FR
Item
641
Protein
PPARgamma
Organism
Human
Assay Sub Type
Binding
Family
NHR
Name
AR Human Androgen NHR Binding Agonist Radioligand LeadHunter Assay - FR
Item
933
Protein
AR
Organism
Human
Assay Sub Type
Binding
Testing Information
Test Sample Requirements:
Minimum for Screen : 225 µl of 10mM stock -OR- 1.13 mg (pre-weighed) for 10µM final testing.
Turnaround Time
Standard:
15 Business Days
Additional Information
Brand:
SafetyScreen
Testing Location:
France - Celle L'Evescault
Questions? Contact Us
You can easily get in touch with a Eurofins Discovery Expert or get help from our Customer Service team. Reach out with questions, or to discuss your specific discovery challenges.
