Biological Information

Family:

Other

Class:

Other

Organism:

Rat

Tissue:

Brain

Assay Information

Assay Type:

Biochemical

Assay Sub Type:

Binding

Detection Method:

Radiometric

Measured Response:

Scintillation

Testing Information

Ligand:

[3H]GABA

Ligand Kd (nM):

15

Ligand Concentration:

10 nM

Non Specific:

100 µM GABA

Incubation:

60 min at RT

Control Inhibitor:

4-aminobutyric acid

Test Concentration / Dose:

Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.

Test Sample Requirements:

Minimum for 1) Screen: 60 µl of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM final testing. 2) Dose Response: 90 µl of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.

Minimum Order Quantity:

2

Turnaround Time

Standard:

10 Business Days

Reference Compound Data

PubChem ID

119

Name

4-aminobutyric acid

Measurement

38nM - IC50

PubChem ID

2284

Name

Baclofen

Measurement

320nM - IC50

PubChem ID

4266

Name

Muscimol

Measurement

200nM - IC50

Clinical Relevance

Therapeutic Area:

CNS/Addiction/Pain

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault

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