Biological Information

Background Information:

Evaluation of the agonist activity of compounds at the human GLP-1 receptor, determined by measuring their effect on cAMP production.

Family:

GPCR

Sub Family:

Glucagon

Class:

Class B

Protein Name:

GLP-1

Uniprot Number:

P43220

Gene Name:

GLP1R

Gene ID:

2740

Gene Aliases:

GLP-1-R GLP-1R

Organism:

Human

Assay Information

Assay Type:

Functional

Assay Sub Type:

Cell Based

Functional Mode:

Agonist

Detection Method:

HTRF

Testing Information

Incubation:

30 min at 37°C

Control Activator:

GLP-1(7-37)

Minimum Order Quantity:

16

Turnaround Time

Standard:

15 Business Days

Reference Compound Data

PubChem ID

16133830

Name

GLP-1(7-37)

Measurement

0.85nM - EC50

PubChem ID

171378578

Name

Retatrutide

Measurement

0.944nM - EC50

PubChem ID

156588324

Name

Tirzépatide

Measurement

4.52nM - EC50

PubChem ID

56843331

Name

Semaglutide

Measurement

1.1nM - EC50

PubChem ID

488287462

Name

GLP2(1-34)

Measurement

- EC50

PubChem ID

16134956

Name

Liraglutide

Measurement

3.4nM - EC50

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault

RELATED SOLUTIONS

Item: G432