Biological Information

Background Information:

Evaluation of the antagonist activity of compounds at the human GLP-1 receptor, determined by measuring their effect on agonist-induced cAMP production.

Family:

GPCR

Sub Family:

Glucagon

Class:

Class B

Protein Name:

GLP-1

Uniprot Number:

P43220

Gene Name:

GLP1R

Gene ID:

2740

Gene Aliases:

GLP-1-R GLP-1R

Organism:

Human

Assay Information

Assay Type:

Functional

Assay Sub Type:

Cell Based

Functional Mode:

Antagonist

Detection Method:

HTRF

Testing Information

Incubation:

30 min at 37°C

Minimum Order Quantity:

16

Turnaround Time

Standard:

15 Business Days

Reference Compound Data

PubChem ID

5311276

Name

L-168,049

Measurement

- IC50

PubChem ID

16198321

Name

exendin-3(9-39)

Measurement

313nM - IC50

PubChem ID

16133829

Name

[Des-His1, Glu9]-Glucagon amide

Measurement

- IC50

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault

RELATED SOLUTIONS

Item: G432