Partition coefficient (log D, n-octanol/PBS, pH 7.4) - US
OVERVIEW
DOCUMENTS/REFERENCES
Biological Information
Background Information:
The partition coefficient between water or buffer and n-octanol is the most widely used measure of chemical compound lipophilicity, an key physicochemical parameter governing both pharmacokinetics and pharmacodynamics of drugs. Eurofins has a high-throughput microplate assay using a shake-flask technique in and LCUV analysis for the determination of this important indicator of a successful drug.
Assay Information
Assay Type:
Physiochemical
Detection Method:
HPLC-UV/VIS
Measured Response:
Peak Area Response
Testing Information
Incubation:
60 min at Room Temperature
Test Sample Requirements:
Minimum for 1) Screen: 100 µl of 10 mM stock -OR- 1 to 2 mg (pre-weighed). 2) Dose Response: 250 µl of 10 mM stock -OR- 1.5 to 2 mg (pre-weighed).
Turnaround Time
Standard:
15 Business Days
Additional Information
Brand:
Cerep
Testing Location:
USA - St Charles, MO
Questions? Contact Us
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