OVERVIEW
DOCUMENTS/REFERENCES
Biological Information
Background Information:
The binding of therapeutic compounds to plasma or serum proteins is a reversible, saturable process which can be an important factor in assessing the pharmacokinetic and pharmacodynamics profile of a drug. The extent of a drug’s binding to plasma and serum proteins is a determinant of drug distribution and elimination and is used as a factor in calculating in vivo hepatic clearance based on in vitro clearance The Eurofins assay uses equilibrium dialysis technique in a microplate format to determine the bound and unbound fraction and calculate the percentage of test compound binding to plasma proteins.
Organism:
Human
Construct Details:
Endogenous
Assay Information
Assay Type:
Physiochemical
Detection Method:
HPLC-MS/MS
Measured Response:
Peak Area Response
Testing Information
Incubation:
4 hr at 37°C
Turnaround Time
Standard:
10 Business Days
Additional Information
Brand:
Cerep
Testing Location:
USA - St Charles, MO
Questions? Contact Us
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