SETD7 / SET9 Human Histone Methyltransferase (HMT) Enzymatic LeadHunter Assay - FR

Background Information:

Histone methyl transferases catalyze the transfer of methyl groups to arginine and lysine groups of histones. There are two major histone methyl transferases: Lysine and arginine specific, both need S-Adenosyl methionine as a cofactor (methyl group donor). Histone methy transferases regulate gene expression by modulation of DNA packaging into chromatin; post-translational modifications of histones via methylation control chromatin structure, DNA accessibility, and recruitment of regulatory factors during transcription. Histone methylation plays an important epigenetic role by propagating chromatin states and gene expression patterns from mother to daughter cells.

Family:

Epigenetic

Sub Family:

Histone Methyltransferase (HMT)

Class:

Writer

Protein Name:

SETD7 / SET9

Uniprot Number:

Q8WTS6

Gene Name:

SETD7

Gene ID:

80854

Gene Aliases:

KIAA1717|SET7|SET7/9|Set9|KMT7

Accession Number:

NM_030648

Organism:

Human

Construct Details:

Recombinant