Src Human TK Kinase KINOMEscan ELECT Binding LeadHunter Assay - US

Background Information:

Src family tyrosine kinases are nonreceptor tyrosine kinases that are functionally linked to some receptor-type tyrosine kinases, G-protein-coupled receptors, cytokine receptors, and cell adhesion molecules/receptors. Src family tyrosine kinases are membrane-associated proteins having Src homology 2 (SH2) and SH3 domains, which are important for protein-protein interaction. The activity of Src family tyrosine kinases is regulated through intramolecular interaction between the SH2 domain and the phosphorylated tyrosine at the C-terminal regulatory site (Tyr-527).

Family:

Kinase

Sub Family:

TK

Class:

Protein Tyrosine

Protein Name:

Src

Uniprot Number:

P12931

Protein Aliases:

Proto-oncogene c-Src|pp60c-src|p60-Src

Gene Name:

SRC

Gene ID:

6714

Gene Aliases:

ASV|c-src

Accession Number:

NP_005408.1

Organism:

Human

Construct Details:

Wild Type; Partial Length (Start/Stop: L240/L536); Bacterial Expression