SUV39H1 Human Histone Methyltransferase (HMT) Enzymatic LeadHunter Assay - TW

Background Information:

Histone methyl transferases catalyze the transfer of methyl groups to arginine and lysine groups of histones. There are two major histone methyl transferases: Lysine and arginine specific, both need S-Adenosyl methionine as a cofactor (methyl group donor). Histone methy transferases regulate gene expression by modulation of DNA packaging into chromatin; post-translational modifications of histones via methylation control chromatin structure, DNA accessibility, and recruitment of regulatory factors during transcription. Histone methylation plays an important epigenetic role by propagating chromatin states and gene expression patterns from mother to daughter cells.

Family:

Epigenetic

Sub Family:

Histone Methyltransferase (HMT)

Class:

Writer

Protein Name:

SUV39H1

Uniprot Number:

O43463

Gene Name:

SUV39H1

Gene ID:

6839

Gene Aliases:

KMT1A

Accession Number:

NM_003173

Organism:

Human

Construct Details:

Fragment (2-end), Recombinant