OVERVIEW
DOCUMENTS/REFERENCES
Biological Information
Background Information:
cAMP Hunter™ Gs cell lines overexpress naturally Gs coupled, wild type GPCRs and are designed to detect increases in intracellular cAMP levels in response to agonist stimulation of the receptor. These cell lines are designed to be used in conjunction with the HitHunter® cAMP Assay Detection Kit.
Family:
GPCR
Sub Family:
Bile Acid
Class:
Class A
Coupling:
Gs
Protein Name:
TGR5
Uniprot Number:
Q8TDU6
Protein Aliases:
hGPCR19|Membrane-type receptor for bile acids|M-BAR|hBG37|BG37
Gene Name:
GPBAR1
Gene ID:
151306
Gene Aliases:
BG37|GPCR|TGR5|M-BAR|GPCR19|GPR131|MGC40597
Accession Number:
NM_001077194.1
Organism:
Human
Cell Type:
CHO-K1
Assay Information
Assay Type:
Functional
Assay Sub Type:
Cell Based
Functional Mode:
Antagonist
Testing Information
Control Activator:
TGR5 Receptor Agonist
Test Concentration / Dose:
Eurofins will provide IC/EC50 calculation if 10 concentrations are selected
Test Sample Requirements:
40uL of a 1000X stock for the first assay and 2uL for each additional assay (assay = 1 target, 1 readout, 1 mode)
Minimum Order Quantity:
20
Turnaround Time
Standard:
15 Business Days
Additional Information
Brand:
LeadHunter
Testing Location:
USA - Fremont, CA
Questions? Contact Us
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