Biological Information

Family:

Ion Channel

Sub Family:

Transient Potential

Class:

Voltage-Gated

Protein Name:

TRPM8

Uniprot Number:

Q7Z2W7

Gene Name:

TRPM8

Gene ID:

79054

Accession Number:

NM_024080

Organism:

Human

Construct Details:

Recombinant

Cell Type:

293H

Assay Information

Assay Type:

Functional

Assay Sub Type:

Cell Based

Functional Mode:

Antagonist

Detection Method:

Fluorimetry

Measured Response:

Fluorescence

Testing Information

Incubation:

RT

Control Inhibitor:

BCTC

Control Activator:

icilin (100 nM)

Test Concentration / Dose:

Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.

Test Sample Requirements:

Minimum for 1) Screen: 225 μl of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM final testing. 2) Dose Response: 280 μl of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.

Minimum Order Quantity:

16

Turnaround Time

Standard:

15 Business Days

Reference Compound Data

PubChem ID

2733484

Name

Capsazepine

Measurement

14000nM - IC50

PubChem ID

9929425

Name

BCTC

Measurement

660nM - IC50

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault

RELATED SOLUTIONS

Item: 3316
Item: G185
Item: P424