RESOURCES

Eurofins Discovery Ion Channel Services Overview

Voltage-gated sodium channels (Na_vs) play a crucial electrical signaling role in neurons.

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Helicases are specialized, essential enzymes that unwind double-stranded DNA-DNA or RNA-DNA duplexes, which is critical for many vital cellular processes.

Obesity is a serious, chronic disease currently affecting about 38% of the global population and expected to rise to over 50% by 2035 according to a recent report from the World Obesity Atlas (WOA).

Introducing a wide and deep set of robust data determined in validated assays for a foundational collection of drugs, drug failures, and pharmacological tools.

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Drug failures from Preclinical and Clinical gap

The Comprehensive in vitro Proarrhythmia Assay (CiPA) initiative is an effort to improve the accuracy of proarrhythmic risk assessment by reducing the focus on in vitro hERG channel assays and in vivo QT interval measurements.

Carcinogenicity animal studies are the most time- and resource-consuming studies in toxicology, but the relevance to humans is often questionable.

Neurotoxicity is one of the major concerns in central nervous system (CNS) drug discovery and is a frequent cause of attrition in clinical trials or approved drug withdrawal.