Reaction Optimization and Medium-size 100-1k Collection of Compounds in Drug Discovery

Our Eurofins Discovery synthetic chemistry teams can leverage our High-Throughput Experimentation (HTE) lab to rapidly screen and improve key synthetic transformations. Employing flow chemistry and photoredox systems in combination with parallelization techniques enables the rapid discovery of optimal conditions that can be applied to accelerate your project and delivery of target molecules.
 
Taking it one step further, our automated Chemspeed robotic platform is capable of performing multistep library synthesis, catalyst kit preparation for screening of conditions, reaction optimization, and sample preparation with complete control through a computer interface. The system is able to handle both solid and liquid dispensing with high degrees of accuracy, control reaction temperatures from -20ºC to 150ºC, and provide a large inert atmosphere for 48 parallel reactors. Automated workups including evaporation, filtration, liquid–liquid extraction, and solid-phase extraction (SPE) can be performed and coupled with our high-throughput purification facilities to deliver high-quality compounds and reduce cycle time – saving you time and money.
 
Production of small molecules libraries in 5-15 mg as dry powdered samples with quick turnaround time: Gain the advantage of our experience in organic synthesis to connect you with the best resources to fit your current project needs, including design of automated multistep synthesis with our Parallel Medicinal Chemistry (PMC) program.