Eurofins Discovery offers a large menu of cell-based nuclear hormone receptor (NHR) assays to examine the effects of chemicals, drugs, and nutrients on nuclear receptor activity. We offer over 20 different cellular assays that monitor receptor activation by either nuclear translocation or NHR co-activator interaction — but without the lengthy compound incubation times inherent with traditional reporter gene assays. Screen compounds against our complete panel of assays or select your own customized group of receptors based on therapeutic relevance (Toxicology, Metabolic Diseases, Endocrinology). Our experienced and highly qualified service team will provide you the data you need, quickly and without depleting your own internal resources to allow you to meet your project needs.
Comprehensive Menu
Powered by the PathHunter® technology from DiscoverX, our NHR assays are whole cell, functional assays that measure NHR translocation and NHR-coactivator interaction. Unlike standard reporter gene assays, these assays are chemiluminescent. And they provide fast turnaround, not requiring lengthy 16-24 hours compound incubations, making them ideal assays for screening and profiling.
