Elevate your drug discovery program with our cutting-edge synthetic chemistry solutions. Our holistic approach supports preclinical research by delivering custom, scalable, and efficient synthesis methods that drive your projects forward—from molecule design to IND-enabling production.
Transformative Solutions in Synthetic Chemistry
Tailored Synthesis for Complex Molecules
Our expert team designs robust and reproducible synthetic routes that meet the unique needs of therapeutic modalities such as:
- Peptides, covalent inhibitors, and macrocycles
- Bifunctional degraders and prodrugs
- ADC linkers, PROTACs, and molecular glues
Using a tailored approach, we optimize reaction pathways to ensure smooth scale-up from laboratory prototypes to production-level quantities.
Accelerated Process Optimization
Experience a faster transition from hit-to-lead and lead optimization with our process-focused strategies:
- IND-Enabling Studies: Streamlined methods that facilitate regulatory toxicology and manufacturing scale-up.
- Rapid Iteration: Seamless collaboration with discovery, medicinal, and computational chemists accelerates the refinement of lead compounds.
Comprehensive Synthetic Services
Benefit from over 20 years of industry expertise and a full spectrum of synthetic chemistry services:
- Core Services:
-
- Synthesis of building blocks, key intermediates, and reference compounds
- Creation of stable metabolites and custom libraries
- Production of stable isotopes (15N, 13C, Deuterium chemistry)
- Specialized Expertise:
-
- Heterocyclic chemistry, carbohydrate, lipid, and steroid synthesis
- Advanced peptide synthesis (linear, cyclic, branched, lactam, stapled)
- Microwave-assisted synthesis and dye & sulphur chemistry
- High Throughput & Parallel Synthesis: Utilizing rapid SFC purification and automated robotics labs for targeted library synthesis.
- Advanced Equipment: Cutting-edge flow chemistry, photoredox systems, and a dedicated High Potency Lab ensure safe and efficient chemical containment.
- Integrated Operations: Co-location with ADME teams supports swift DMTA, ensuring your discovery process remains agile and responsive.
- Proven Expertise: Two decades of supporting drug discovery initiatives, with a proven track record in hit-to-lead and lead optimization.
- Collaborative Innovation: We work closely with your research teams to deliver customized solutions that match your scientific goals.
- Scalability and Precision: From milligrams to kilograms, our synthesis routes are designed for reproducibility and efficient scale-up.
State-of-the-Art Technology & Facilities
Our modern facilities empower us to meet your most challenging synthetic chemistry demands:
Why Partner with Us?
Accelerate Your Drug Discovery Journey
Embrace the future of drug discovery with our innovative synthetic chemistry solutions. Let our expertise transform your challenges into opportunities for breakthrough innovations.
Contact us today to learn how we can power your next research success!
