Biological Information

Family:

Ion Channel

Sub Family:

Transient Potential

Class:

Voltage-Gated

Protein Name:

TRPV1

Uniprot Number:

Q8NER1

Gene Name:

TRPV1

Gene ID:

7442

Accession Number:

NM_018727

Organism:

Human

Construct Details:

Recombinant

Cell Type:

CHO-S

Assay Information

Assay Type:

Functional

Assay Sub Type:

Cell Based

Functional Mode:

Agonist

Detection Method:

Fluorimetry

Measured Response:

Fluorescence

Testing Information

Incubation:

RT

Control Activator:

Capsaicin

Test Concentration / Dose:

Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.

Test Sample Requirements:

Minimum for 1) Screen: 225 μl of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM final testing. 2) Dose Response: 280 μl of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.

Minimum Order Quantity:

16

Turnaround Time

Standard:

15 Business Days

Reference Compound Data

PubChem ID

1548943

Name

Capsaicin

Measurement

4.5nM - EC50

PubChem ID

5311093

Name

olvanil

Measurement

13.9nM - EC50

PubChem ID

5702546

Name

UNII-A5O6P1UL4I

Measurement

6.6nM - EC50

PubChem ID

6604822

Name

AM 404

Measurement

443nM - EC50

Clinical Relevance

Therapeutic Area:

CNS/Addiction/Pain

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault

RELATED SOLUTIONS

Item: 1641
Item: G106
Item: P425