Biological Information

Family:

Ion Channel

Sub Family:

Transient Potential

Class:

Voltage-Gated

Protein Name:

TRPV1

Uniprot Number:

Q8NER1

Gene Name:

TRPV1

Gene ID:

7442

Accession Number:

NM_018727

Organism:

Human

Construct Details:

Recombinant

Cell Type:

CHO-S

Assay Information

Assay Type:

Functional

Assay Sub Type:

Cell Based

Functional Mode:

Antagonist

Detection Method:

Fluorimetry

Measured Response:

Fluorescence

Testing Information

Incubation:

RT

Control Inhibitor:

capsazepine

Control Activator:

capsaicin (30 nM)

Test Concentration / Dose:

Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.

Test Sample Requirements:

Minimum for 1) Screen: 225 μl of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM final testing. 2) Dose Response: 280 μl of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.

Minimum Order Quantity:

16

Turnaround Time

Standard:

15 Business Days

Reference Compound Data

PubChem ID

680502

Name

AMG 9810

Measurement

2330nM - IC50

PubChem ID

2733484

Name

Capsazepine

Measurement

60nM - IC50

PubChem ID

16218584

Name

11103-72-3

Measurement

210nM - IC50

Clinical Relevance

Therapeutic Area:

CNS/Addiction/Pain

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault

RELATED SOLUTIONS

Item: 1640
Item: G106