NK3 Human Tachykinin GPCR Cell Based Antagonist Calcium Flux LeadHunter Assay - FR

Background Information:

Tachykinins belong to the superfamily of G protein-coupled seven transmembrane proteins. G-protein-coupled receptors constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. Tachykinin receptors are found in most peripheral tissue and within the central nervous system.

Family:

GPCR

Sub Family:

Tachykinin

Class:

Class A

Protein Name:

NK3

Uniprot Number:

P29371

Protein Aliases:

neurokinin beta receptor

Gene Name:

TACR3

Gene ID:

6870

Gene Aliases:

NK3R|TAC3R

Accession Number:

NM_001059

Organism:

Human

Construct Details:

Recombinant

Cell Type:

CHO-K1