Biological Information

Family:

GPCR

Sub Family:

Formylpeptide

Class:

Class A

Protein Name:

FPR1

Uniprot Number:

P21462

Protein Aliases:

N-formyl peptide receptor|FPR|N-formylpeptide chemoattractant receptor

Gene Name:

FPR1

Gene ID:

2357

Gene Aliases:

FPR|FMLP

Accession Number:

NM_002029

Organism:

Human

Construct Details:

Recombinant

Cell Type:

CHO-K1

Assay Information

Assay Type:

Functional

Assay Sub Type:

Cell Based

Functional Mode:

Agonist

Detection Method:

HTRF

Testing Information

Incubation:

10 min at 37°C

Control Activator:

fMLP

Test Concentration / Dose:

Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.

Test Sample Requirements:

Minimum for 1) Screen: 60 µL of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM finµL testing. 2) Dose Response: 90 µL of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.

Minimum Order Quantity:

16

Turnaround Time

Standard:

15 Business Days

Reference Compound Data

PubChem ID

457933

Name

WKYMVM

Measurement

538nM - EC50

PubChem ID

Name

fMLP

Measurement

0.24nM - EC50

PubChem ID

Name

C5a

Measurement

217nM - EC50

Clinical Relevance

Therapeutic Area:

Inflammation/Allergy

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault

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