FPR1 Human Formylpeptide GPCR Binding Agonist Radioligand LeadHunter Assay - FR

Item: 407

Price: Login to View Pricing

Status: Available

ADD TO CART

OVERVIEW

DOCUMENTS/REFERENCES

Biological Information

Family:

GPCR

Sub Family:

Formylpeptide

Class:

Class A

Protein Name:

FPR1

Uniprot Number:

P21462

Protein Aliases:

N-formyl peptide receptor|FPR|N-formylpeptide chemoattractant receptor

Gene Name:

FPR1

Gene ID:

2357

Gene Aliases:

FPR|FMLP

Accession Number:

NM_002029

Organism:

Human

Construct Details:

Recombinant

Assay Information

Assay Type:

Biochemical

Assay Sub Type:

Binding

Detection Method:

Radiometric

Measured Response:

Scintillation

Testing Information

Ligand:

[3H]fMLP

Ligand Kd (nM):

Ligand Concentration:

0.4 nM

Non Specific:

1 µM FMLP

Incubation:

60 min at 4°C

Control Inhibitor:

fMLP

Test Concentration / Dose:

Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.

Test Sample Requirements:

Minimum for 1) Screen: 60 µl of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM final testing. 2) Dose Response: 90 µl of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.

Minimum Order Quantity:

Turnaround Time

Standard:

15 Business Days

Reference Compound Data

PubChem ID

457933

Name

WKYMVM

Measurement

1nM - IC50

PubChem ID

Name

fMLP

Measurement

0.93nM - IC50

Clinical Relevance

Therapeutic Area:

Inflammation/Allergy

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault