Biological Information
Family:
GPCR
Sub Family:
Glucagon
Class:
Class B
Protein Name:
GLP-1
Uniprot Number:
P43220
Protein Aliases:
GLP-1-R|GLP-1R
Gene Name:
GLP1R
Gene ID:
2740
Accession Number:
NM_002062
Organism:
Mouse
Cell Type:
Beta TC6
Assay Information
Assay Type:
Functional
Assay Sub Type:
Cell Based
Functional Mode:
Antagonist
Detection Method:
HTRF
Testing Information
Incubation:
10 min at RT
Control Inhibitor:
exendin-3(9-39)
Control Activator:
GLP-1(7-37) (0.3 nM)
Test Concentration / Dose:
Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.
Test Sample Requirements:
Minimum for 1) Screen: 60 µL of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM finµL testing. 2) Dose Response: 90 µL of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.
Minimum Order Quantity:
16
Turnaround Time
Standard:
15 Business Days
Reference Compound Data
Clinical Relevance
Therapeutic Area:
Metabolic Diseases
Additional Information
Brand:
LeadHunter
Testing Location:
France - Celle L'Evescault
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