Biological Information

Family:

GPCR

Sub Family:

Glucagon

Class:

Class B

Protein Name:

GLP-1

Uniprot Number:

P43220

Protein Aliases:

GLP-1-R|GLP-1R

Gene Name:

GLP1R

Gene ID:

2740

Accession Number:

NM_002062

Organism:

Mouse

Cell Type:

Beta TC6

Assay Information

Assay Type:

Functional

Assay Sub Type:

Cell Based

Functional Mode:

Antagonist

Detection Method:

HTRF

Testing Information

Incubation:

10 min at RT

Control Inhibitor:

exendin-3(9-39)

Control Activator:

GLP-1(7-37) (0.3 nM)

Test Concentration / Dose:

Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.

Test Sample Requirements:

Minimum for 1) Screen: 60 µL of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM finµL testing. 2) Dose Response: 90 µL of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.

Minimum Order Quantity:

16

Turnaround Time

Standard:

15 Business Days

Reference Compound Data

PubChem ID

5311276

Name

L-168,049

Measurement

- IC50

PubChem ID

16133829

Name

110084-95-2

Measurement

- IC50

PubChem ID

Name

exendin-3(9-39)

Measurement

4nM - IC50

Clinical Relevance

Therapeutic Area:

Metabolic Diseases

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault

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