Biological Information
Family:
GPCR
Sub Family:
Glucagon
Class:
Class B
Protein Name:
GLP-1
Uniprot Number:
P43220
Protein Aliases:
GLP-1-R|GLP-1R
Gene Name:
GLP1R
Gene ID:
2740
Accession Number:
NM_002062
Organism:
Mouse
Assay Information
Assay Type:
Biochemical
Assay Sub Type:
Binding
Detection Method:
Radiometric
Measured Response:
Scintillation
Testing Information
Ligand:
[125I]GLP-1(7-36)
Ligand Kd (nM):
0.1
Ligand Concentration:
0.025 nM
Non Specific:
1 µM GLP-1(7-36)
Incubation:
120 min at 37°C
Control Inhibitor:
Exendin 4
Test Concentration / Dose:
Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.
Test Sample Requirements:
Minimum for 1) Screen: 60 µl of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM final testing. 2) Dose Response: 90 µl of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.
Minimum Order Quantity:
2
Turnaround Time
Standard:
15 Business Days
Reference Compound Data
Clinical Relevance
Therapeutic Area:
Metabolic Diseases
Additional Information
Brand:
LeadHunter
Testing Location:
France - Celle L'Evescault
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