NK1 Human Tachykinin GPCR Cell Based Agonist Calcium Flux LeadHunter Assay - FR

Background Information:

Tachykinins belong to the superfamily of G protein-coupled seven transmembrane proteins. G-protein-coupled receptors constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. Tachykinin receptors are found in most peripheral tissue and within the central nervous system.

Family:

GPCR

Sub Family:

Tachykinin

Class:

Class A

Protein Name:

NK1

Uniprot Number:

P25103

Protein Aliases:

NK-1 receptor|NK-1R|Tachykinin receptor 1

Gene Name:

TACR1

Gene ID:

6869

Gene Aliases:

SPR|NK1R|NKIR|TAC1R

Accession Number:

NM_001058

Organism:

Human

Cell Type:

U373 MG