Biological Information

Family:

GPCR

Sub Family:

Parathyroid Hormone

Class:

Class B

Protein Name:

PTH1

Uniprot Number:

Q03431

Protein Aliases:

PTH/PTHr receptor|Parathyroid hormone 1 receptor|PTH1 receptor

Gene Name:

PTH1R

Gene ID:

5745

Accession Number:

NM_000316

Organism:

Human

Cell Type:

Saos-2

Assay Information

Assay Type:

Functional

Assay Sub Type:

Cell Based

Functional Mode:

Antagonist

Detection Method:

HTRF

Testing Information

Incubation:

10 min at RT

Control Inhibitor:

PTHrP (7-34)

Control Activator:

PTHrP (1-34) (1 nM)

Test Concentration / Dose:

Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.

Test Sample Requirements:

Minimum for 1) Screen: 60 µL of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM finµL testing. 2) Dose Response: 90 µL of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.

Minimum Order Quantity:

16

Turnaround Time

Standard:

15 Business Days

Reference Compound Data

PubChem ID

Name

PTHrP (7-34)

Measurement

84nM - IC50

PubChem ID

Name

[Asn10,Leu11,D-Trp12]PTHrP (7-34)

Measurement

3.4nM - IC50

PubChem ID

Name

Tip 39

Measurement

140nM - IC50

Additional Information

Brand:

LeadHunter

Testing Location:

France - Celle L'Evescault

RELATED SOLUTIONS

Item: 2660
Item: G130