Biological Information
Family:
GPCR
Sub Family:
Cannabinoid
Class:
Class A
Protein Name:
CB1
Uniprot Number:
P21554
Gene Name:
CNR1
Gene ID:
1268
Gene Aliases:
CB1K5|CB-R|CB1|CANN6|CB1A
Accession Number:
X54937
Organism:
Human
Construct Details:
Recombinant
Assay Information
Assay Type:
Biochemical
Assay Sub Type:
Binding
Detection Method:
Radiometric
Measured Response:
Scintillation
Testing Information
Ligand:
[3H]CP 55940
Ligand Kd (nM):
0.9
Ligand Concentration:
2 nM
Non Specific:
AM281 (10 µM)
Incubation:
30 min at RT
Control Inhibitor:
CP55940
Test Concentration / Dose:
Eurofins will provide IC/EC50 calculation if 5 or more concentrations are selected.
Test Sample Requirements:
Minimum for 1) Screen: 60 μl of 10 mM stock -OR- 1 mg (pre-weighed) for 10µM final testing. 2) Dose Response: 90 μl of 10 mM stock -OR- 1 mg (pre-weighed) for a top concentration at 10 µM.
Minimum Order Quantity:
2
Turnaround Time
Standard:
10 Business Days
Reference Compound Data
Clinical Relevance
Therapeutic Area:
CNS/Addiction/Pain
Additional Information
Brand:
LeadHunter
Testing Location:
France - Celle L'Evescault
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