A2A Human Adenosine GPCR Cell Based Antagonist cAMP LeadHunter Assay - TW

Background Information:

Adenosine receptors belong to the superfamily of G protein-coupled seven transmembrane proteins. G-protein-coupled receptors constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. Adenosine receptors may also be called P1 receptors, which are distinguished from transmitter-gated ion channels (P2X receptors) and G protein-coupled receptors (P2Y).

Family:

GPCR

Sub Family:

Adenosine

Class:

Class A

Protein Name:

A2A

Uniprot Number:

P29274

Gene Name:

ADORA2A

Gene ID:

135

Gene Aliases:

RDC8|ADORA2

Accession Number:

NM_000675

Organism:

Human

Construct Details:

Full Length, Recombinant

Cell Type:

HEK293