V1B Human Vasopressin / Oxytocin GPCR Cell Based Antagonist Calcium Flux LeadHunter Assay - FR

Background Information:

Vasopressin receptors belong to the superfamily of G protein-coupled seven transmembrane proteins. G-protein-coupled receptors constitute one of the major signal transduction systems in eukaryotic cells. Coding sequences for these receptors, in those regions believed to contribute to the agonist-antagonist binding site, are strongly conserved across mammalian species. Vasopressin receptors are currently classified into V1A, V1B (V3) and V2 subtypes. The V1B receptor is known to be present only in the adenohypophysis.

Family:

GPCR

Sub Family:

Vasopressin and Oxytocin

Class:

Class A

Protein Name:

V1B

Uniprot Number:

P47901

Protein Aliases:

AVPR V1b|AVPR V3|Antidiuretic hormone receptor 1b|Vasopressin V3 receptor

Gene Name:

AVPR1B

Gene ID:

553

Gene Aliases:

AVPR3|VPR3

Accession Number:

NM_000707

Organism:

Human

Construct Details:

Recombinant

Cell Type:

Chem-1